Surviving a life-threatening 2,4-DNP intoxication: 'Almost dying to be thin'.
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چکیده
منابع مشابه
Role for draTG and rnf genes in reduction of 2,4-dinitrophenol by Rhodobacter capsulatus.
The phototrophic bacterium Rhodobacter capsulatus is able to reduce 2,4-dinitrophenol (DNP) to 2-amino-4-nitrophenol enzymatically and thus can grow in the presence of this uncoupler. DNP reduction was switched off by glutamine or ammonium, but this short-term regulation did not take place in a draTG deletion mutant. Nevertheless, the target of DraTG does not seem to be the nitrophenol reductas...
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Background and purpose: 2, 4-dinitrophenol (2,4-DNP) is categorized as one of the priority pollutants that is used in pharmaceutical and chemical industries, pesticides, etc. In this study we aimed at investigating the biodegradation of 2,4-DNP by immobilized laccase on nano-porous silica beads. Materials and methods: An experimental study was conducted in which the enzyme was chemically cro...
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Background: Phenol and nitrophenol are common compounds found in different types of industrial wastewater known as serious threats to human health and natural environment. In this study, Daphnia magna was used to evaluate the effectiveness of "baffle fixes film up flow sludge blanket filtration" (BFUSBF) system in elimination of phenolic compounds from water. Methods: D. magna cult...
متن کاملThe characterization fo the B-cell repertoire specific for the 2,4- dinitrophenyl and 2,4,6-trinitrophenyl determinants in neonatal BALB/c mice
The (B-cell) repertoire responsive to the DNP and TNP haptenic determinants in BALB/c neonates was analyzed in terms of the specificity of stimulation of neonatal B cells as well as the diversity of specificities available in neonatal populations. The results indicate that the parameters of stimulation of neonatal B cells are similar to those of nonimmune adults, particularly in the exquisitely...
متن کاملThe chemical uncoupler 2,4-dinitrophenol (DNP) protects against diet-induced obesity and improves energy homeostasis in mice at thermoneutrality.
The chemical uncoupler 2,4-dinitrophenol (DNP) was an effective and widely used weight loss drug in the early 1930s. However, the physiology of DNP has not been studied in detail because toxicity, including hyperthermia and death, reduced interest in the clinical use of chemical uncouplers. To investigate DNP action, mice fed a high fat diet and housed at 30 °C (to minimize facultative thermoge...
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عنوان ژورنال:
- The Netherlands journal of medicine
دوره 69 3 شماره
صفحات -
تاریخ انتشار 2011